export functions:            

Pathway details: 2,4,6-trinitrotoluene degradation

General info Interaction details Linked pathways Protein-protein interactions
  Pathway was created on Mon Jul 29, 2013.
 Contributed by aracyc:
The 2,4,6-trinitrotoluene (TNT), a nitroaromatic explosive, is a highly persistent, organic pollutant, introduced into the environment from the industries involved in the manufacture, packaging, use and decommissioning of explosives. It is a primary target for remediation because of its toxicity (it is a designated class-C carcinogen) and the global extent of environmental contamination. Phytoremidiation is emerging as a viable alternative strategy to the current methods. With their extensive root system, plants have a remarkable ability to extract compounds from their surroundings. Although several studies have investigated the tolerance of plants to TNT and the active uptake of TNT by plant roots has been demonstrated |CITS: [Pavlostathis98]|, very little is known about the molecular and biochemical basis of its detoxification in the plants. A recent study has demonstrated the reductive transformation of TNT to give hydroxylaminodinitrotoluene (HADNT), and then aminodinitrotoluene (ADNT) and their glucosides .
  Parts of this pathway occur in:   cytosol     nucleus  

View raw
Browse interactions [58]: By type By location All interactions
Enzymatic reaction
Participating entities and compounds
Linked pathways
Browse entities [83]: By type Sources & sinks All entities

metabolite [20]
RNA [17]
polypeptide [17]
gene [17]
protein complex [12]

Copyright © 2006-2016 Wurtele lab. Copyright refers to the integration and online application, not the data from the various sources.


Number of queries executed: 10