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MetNet - plant pathway - glycolysis II (from fructose-6P)
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Pathway details: glycolysis II (from fructose-6P)

General info Interaction details Linked pathways Protein-protein interactions
  Pathway was created on Mon Jul 29, 2013.
 Contributed by aracyc:
General Background Glycolysis, which was first studied as a pathway for the utilization of glucose, is one of the components of central metabolism, the other two being the pentose phosphate pathway and the . As such, its functioning is essential under all conditions of growth because it produces six (β-D-glucose-6-phosphate, D-fructose-6-phosphate, dihydroxyacetone phosphate, 3-phosphoglycerate, phosphoenolpyruvate, and pyruvate) of the 13 precursor metabolites that are the starting materials for the biosynthesis of building blocks for macromolecules and other needed small molecules. Glycolysis can be found, if at least in part, in all organisms. Glycolysis has evolved to fulfill two essential functions: i) it oxidizes hexoses to generate ATP, reductants and pyruvate, and ii) being an amphibolic pathway (pathway that involves both catabolism and anabolism), it can reversibly produce hexoses from various low-molecular weight molecules. Because various degradation pathways feed into glycolysis at many different points, glycolysis or portions of it run in the forward or reverse direction, depending on the carbon source being utilized, in order to satisfy the cell's need for precursor metabolites and energy. This switching of direction is possible because all but two of the enzymatic reactions comprising glycolysis are reversible, and the conversions catalyzed by the two exceptions are rendered functionally reversible by other enzymes ("fructose-1,6-bisphosphatase" and ) that catalyze different irreversible reactions flowing in the opposite direction. About This Pathway The standard glycolysis pathway (glycolysis I (plastidic)) depicts the sugar input into the pathway as glucose. However, the glycolysis pathway is utilized for the degradation of many different types of sugars. This partial depiction of the glycolysis pathway is used with substrates other than glucose, such as , L-sorbose , mannitol , D-sorbitol , and sucrose, which are processed into D-fructose-6-phosphate. D-fructose-6-phosphate enters glycolysis and is processed to the end product pyruvate, which is often fermented further into fermentation products such as ethanol, and acetate.
  Parts of this pathway occur in:   cytosol     plastid stroma     plastid     nucleus     mitochondrion     apoplast   multiple locations  

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Enzymatic reaction
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metabolite [25]
protein complex [19]
RNA [74]
polypeptide [75]
gene [74]

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