Warning: session_start() [function.session-start]: open(C:\Windows\Temp\\sess_t9mm47u3b2kt61m7pb0hbv0jq3, O_RDWR) failed: Invalid argument (22) in D:\inetpub\wwwroot\include\lib_auth.php on line 5

Warning: Cannot modify header information - headers already sent by (output started at D:\inetpub\wwwroot\include\ui_pathway.php:63) in D:\inetpub\wwwroot\include\ui_pathway.php on line 83

Warning: Cannot modify header information - headers already sent by (output started at D:\inetpub\wwwroot\include\ui_pathway.php:63) in D:\inetpub\wwwroot\include\data_organism.php on line 119
MetNet - plant pathway - phloridzin biosynthesis
  export functions:            

Pathway details: phloridzin biosynthesis


General info Interaction details Linked pathways Protein-protein interactions
Notes
  Pathway was created on Mon Jul 29, 2013.
 Contributed by aracyc:
Supporting evidence for this pathway in Arabidopsis: Enzyme(s) that catalyzes one or more of the key reactions in this pathway were predicted in Arabidopsis. [more info] Summary from MetaCyc: is a phenylproponoid derivative also known as phloretin 2-beta glucoside, it is a dihydrochalcone and the structure closely resembles the precursors chalcones . was first discovered in 1835 as a bitter tasting compound in barks of apple trees. Its distribution in the plant kingdom seems more widely present in the Malus species. Tissue distribution of the compound differs considerably; in and Lithocarpus polystachyus it mainly exists in fruits, in it is found in the stem and root barks, young leaves and fruits. The root bark contained more of it than the stem bark . In Malus domestica, 90% of the soluble phenolics in the leaves is that of the dihydrochalcone . This compound has been used for medicinal properties for a long time, modern medicine uses it in the control of blood sugar levels, protective agent to the heart from scavenging oxygen free radicals and antioxidant injuries. Studies have also shown that has estrogenic and antiestrogenic activities |CITS: [ 20410591]|. Dihydrochalcones are related to flavonoids but very less is known about their biosynthetic route, some enzymes have been cloned and it seems to depend on the presence of a dehydrogenase that can convert the substrate from coumaroyl-CoA. No biosynthesis occurs in which is a closely related species of apples. This is due to the absence of the enzyme capable of catalyzing the first step of the biosynthesis namely the formation of from coumaroyl-CoA |CITS: [IND44141307]|.
  Parts of this pathway occur in:   cytosol     nucleus  


interactions
View raw
Browse interactions [23]: By type By location All interactions
Type
Translation
Transcription
Enzymatic reaction
Composition-OR
Catalysis
Participating entities and compounds
Linked pathways
Browse entities [40]: By type Sources & sinks All entities


Copyright © 2006-2016 Wurtele lab. Copyright refers to the integration and online application, not the data from the various sources.

 

Number of queries executed: 10

Warning: Unknown: open(C:\Windows\Temp\\sess_t9mm47u3b2kt61m7pb0hbv0jq3, O_RDWR) failed: Invalid argument (22) in Unknown on line 0

Warning: Unknown: Failed to write session data (files). Please verify that the current setting of session.save_path is correct (C:\Windows\Temp\) in Unknown on line 0