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MetNet - Plant pathway database

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You are in: protein complex > CPLX-7979

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Entity information

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This entity is present in: cytosol
The cDNA encoding |FRAME:CPLX-7979| was isolated from |FRAME: ORG-5993|. The enzyme was initially reported to catalyzes the conversion of |FRAME: ALLANTOATE| to yield |FRAME: CPD-1091| via |FRAME: CPD-598| |CITS: [16496096]|, but a later study showed that the enzyme catalyzes only the first part - conversion of |FRAME: ALLANTOATE| to |FRAME: CPD-598| |CITS: [19935661]| The function of the gene was confirmed by complementation of Saccharomyces cerevisiae |FRAME: YIR029W| mutants, blocked in allantoate degradation. Mutants with T-DNA insertions in |FRAME: AT4G20070|, the gene encoding the enzyme, showed normal growth on standard medium, but growth was completely blocked when the sole N source was allantoin. The enzyme was expressed in all tissues indicating a vital role in metabolism. It was proposed that the enzyme is involved in the purine salvage pathway through ureide biosynthesis and degradation |CITS: [16496096]|. The gene was subsequently cloned, expressed in planta in the form of several StrepII-tagged variants, and highly purified from leaf extracts. The enzyme requires |FRAME:MN+2| and exists as a homodimer |CITS: [18065556]|. [junyoni]
Pathways
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The entity [CPLX-7979] participates in the following pathways:

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Pathway [4 shown] Organism Created on
allantoin degradation to glyoxylate II Arabidopsis Mon Jul 29, 2013
allantoin degradation to glyoxylate III Arabidopsis Mon Jul 29, 2013
allantoin degradation to ureidoglycolate II (ammonia producing) Arabidopsis Mon Jul 29, 2013
superpathway of allantoin degradation in plants Arabidopsis Mon Jul 29, 2013

Interactions
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Type
Composition-AND

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